Reticulocyte subpopulations and reticulocyte maturity index (RMI) rise as body iron status falls
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چکیده
منابع مشابه
Ferrioxamine iron in rabbit reticulocyte heme synthesis.
By M. D. GERLANC, E. J. ZAPOLSKJ, M. Rurnr r AND J. V. Pm aorro P ESFERRIOXAMINE, the sideramine of the Actinomyces, is a potent chelator of ferric iron.1’2 It is believed that all aerobic organisms produce sideramines which function as specific iron donors ( coenzymes ) for the iron incorporating enzyme of the heme synthesis.a.4 I,, light of the role of ferrioxanlines in henle synthesis in mic...
متن کاملRED CELLS, IRON, AND ERYTHROPOIESIS Membrane remodeling during reticulocyte maturation
The transition of reticulocytes into erythrocytes is accompanied by extensive changes in the structure and properties of the plasma membrane. These changes include an increase in shear resistance, loss of surface area, and acquisition of a biconcave shape. The processes by which these changes are effected have remained largely undefined. Here we examine how the expression of 30 distinct membran...
متن کاملPurified azure B as a reticulocyte stain.
A comparison has been made between reticulocyte preparations stained with purified azure B and with several commerically available batches of brilliant cresyl blue and new methylene blue. Marked variations were observed in the composition and staining performances of the various batches of the two commerically available dyes. Although there were no significant differences in reticulocyte counts...
متن کاملReticulocyte maturity as an indicator for estimating qualitative abnormality of erythropoiesis.
AIMS To determine the maturity of reticulocytes in patients with anaemia as a result of various haematological disorders including those with qualitative abnormalities such as ineffective erythropoiesis or dyserythropoiesis. METHODS The number of mature reticulocytes was measured with flow cytometry in venous blood samples from 122 patients with haematological disorders and 100 healthy contro...
متن کاملEarly prediction of response to intravenous iron supplementation by reticulocyte haemoglobin content and high-fluorescence reticulocyte count in haemodialysis patients.
BACKGROUND Optimal response to recombinant human erythropoietin (rHuEpo) in haemodialysis (HD) patients requires provision of sufficient available iron. However, a balance between iron requirements and supplements remains a challenge in clinical practice. Reticulocyte parameters, i.e. reticulocyte haemoglobin content (CHr) and reticulocytes in a high-fluorescence intensity region (HFR), have be...
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ژورنال
عنوان ژورنال: American Journal of Hematology
سال: 2001
ISSN: 0361-8609,1096-8652
DOI: 10.1002/ajh.1091